Integrating the Neurobiology of Schizophrenia

  • Filename: integrating-the-neurobiology-of-schizophrenia.
  • ISBN: 0080475086
  • Release Date: 2007-02-27
  • Number of pages: 480
  • Author:
  • Publisher: Academic Press



This book examines the role that dopamine plays in schizophrenia, examining its role in not only the symptoms of the disease but also in its treatment. It also reviews all neurotransmitters that have been implicated in schizophrenia, exploring the genetic data, clinical data implicating the transmitter, and the preclinical data exploring how a transmitter may interact with dopamine and contribute to the dopaminergic phenotype observed in the illness. This book will serve as an educational tool for instructors, a guide for clinicians, and be of interest to researchers. It is a good reference for researchers specialized in one particular area and interested in learning about other areas of pathology in schizophrenia and how they may all feed into each other. The book concludes with an overall integrative model assembling as many of these elements as possible.

Advances in the Neurobiology of Schizophrenia

  • Filename: advances-in-the-neurobiology-of-schizophrenia.
  • ISBN: 0471952877
  • Release Date: 1995-07-11
  • Number of pages: 482
  • Author: Johan A. den Boer
  • Publisher: Wiley



Internationally renowned experts in schizophrenia present an up-to-date review of this disorder's biological rather than psychological origins. Surveys new drugs for its treatment which are directed at novel biochemical targets in the brain. Includes a clinical profile of newly available therapeutic agents.

The Neurobiology of Schizophrenia

  • Filename: the-neurobiology-of-schizophrenia.
  • ISBN: 9780128018774
  • Release Date: 2016-07-08
  • Number of pages: 468
  • Author: Ted Abel
  • Publisher: Academic Press



The Neurobiology of Schizophrenia begins with an overview of the various facets and levels of schizophrenia pathophysiology, ranging systematically from its genetic basis over changes in neurochemistry and electrophysiology to a systemic neural circuits level. When possible, the editors point out connections between the various systems. The editors also depict methods and research strategies used in the respective field. The individual backgrounds of the two editors promote a synthesis between basic neuroscience and clinical relevance. Provides a comprehensive overview of neurobiological aspects of schizophrenia Discusses schizophrenia at behavioral, cognitive, clinical, electrophysiological, molecular, and genetic levels Edited by a translational researcher and a psychiatrist to promote synthesis between basic neuroscience and clinical relevance Elucidates connections between the various systems depicted, when possible

Behavioral Neurobiology of Schizophrenia and Its Treatment

  • Filename: behavioral-neurobiology-of-schizophrenia-and-its-treatment.
  • ISBN: 3642137172
  • Release Date: 2010-08-19
  • Number of pages: 666
  • Author: Neal R. Swerdlow
  • Publisher: Springer Science & Business Media



This book describes the state-of-the-art of treatment of schizophrenia and reflects its development in 22 chapters written by leading authorities in the field

Neurobiology of Mental Illness

  • Filename: neurobiology-of-mental-illness.
  • ISBN: 9780195189803
  • Release Date: 2005-07-21
  • Number of pages: 1231
  • Author: Dennis S. Charney
  • Publisher: Oxford University Press



The new edition of this definitive textbook reflects the continuing reintegration of psychiatry into the mainstream of biomedical science. The research tools that are transforming other branches of medicine - epidemiology, genetics, molecular biology, imaging, and medicinal chemistry - are also transforming psychiatry. The field stands poised to make dramatic advances in defining disease pathogenesis, developing diagnostic methods capable of identifying specific and valid disease entities, discovering novel and more effective treatments, and ultimately preventing psychiatric disorders. The Neurobiology of Mental Illness is written by world-renowned experts in basic neuroscience and the pathophysiology and treatment of psychiatric disorders. It begins with a succint overview of the basic neurosciences followed by and evaluation of the tools that are available for the study of mental disorders in humans. The core of the book is a series of consistently organized sections on the major psychiatric disorders that cover their diagnostic classification, molecular genetics, functional neuroanatomy, neurochemistry and pharmacology, neuroimaging, and principles of pharmacotherapy. Chapters are written in a clear style that is easily accessible to practicing psychiatrists, and yet they are detailed enough to interest researchers and academics.For this second edition, every section has been thoroughly updated, and 13 new chapters have been added in areas where significant advances have been made, including functional genomics and animal models of illness; epidemiology; cognitive neuroscience; postmortem investigation of human brain; drug discovery methods for psychiatric disorders; the neurobiology of schizophrenia; animal models of anxiety disorders; neuroimaging studies of anxiety disorders; developmental neurobiology and childhood onset of psychiatric disorders; the neurobiology of mental retardation; the interface between neurological and psychiatric disorders; the neurobiology of circadian rhythms; and the neurobiology of sleep disorders. Both as a textbook and a reference work, Neurobiology of Mental Illness represents a uniquely valuable resource for psychiatrists, neuroscientists, and their students or trainees.

The Neurobiology of Criminal Behavior

  • Filename: the-neurobiology-of-criminal-behavior.
  • ISBN: 9781317023142
  • Release Date: 2016-03-03
  • Number of pages: 232
  • Author: Anthony Walsh
  • Publisher: Routledge



The main feature of this work is that it explores criminal behavior from all aspects of Tinbergen's Four Questions. Rather than focusing on a single theoretical point of view, this book examines the neurobiology of crime from a biosocial perspective. It suggests that it is necessary to understand some genetics and neuroscience in order to appreciate and apply relevant concepts to criminological issues. Presenting up-to-date information on the circuitry of the brain, the authors explore and examine a variety of characteristics, traits and behavioral syndromes related to criminal behavior such as ADHD, intelligence, gender, the age-crime curve, schizophrenia, psychopathy, violence and substance abuse. This book brings together the sociological tradition with the latest knowledge the neurosciences have to offer and conveys biological information in an accessible and understanding way. It will be of interest to scholars in the field and to professional criminologists.

Neurobiology of Psychiatric Disorders

  • Filename: neurobiology-of-psychiatric-disorders.
  • ISBN: 9780444520029
  • Release Date: 2012
  • Number of pages: 760
  • Author: Thomas E. Schlaepfer
  • Publisher: Elsevier



This new volume in the Handbook of Clinical Neurology presents a comprehensive review of the fundamental science and clinical treatment of psychiatric disorders. Advances in neuroscience have allowed for dramatic advances in the understanding of psychiatric disorders and treatment. Brain disorders, such as depression and schizophrenia, are the leading cause of disability worldwide. It is estimated that over 25% of the adult population in North America are diagnosed yearly with at least one mental disorder and similar results hold for Europe. Now that neurology and psychiatry agree that all mental disorders are in fact, "brain diseases," this volume provides a foundational introduction to the science defining these disorders and details best practices for psychiatric treatment. *Provides a comprehensive review of the scientific foundations of psychiatric disorders and psychiatric treatment *Includes detailed results from genetics, molecular biology, brain imaging, and neuropathological, immunological, epidemiological, metabolic, therapeutic and historical aspects of the major psychiatric disorders *A “must have? reference and resource for neuroscientists, neurologists, psychiatrists, and clinical psychologists as well as all research scientists investigating disorders of the brain

Neurobiology of Brain Disorders

  • Filename: neurobiology-of-brain-disorders.
  • ISBN: 9780123982803
  • Release Date: 2014-12-03
  • Number of pages: 824
  • Author: Michael J. Zigmond
  • Publisher: Elsevier



Neurobiology of Brain Disorders is the first book directed primarily at basic scientists to offer a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular, and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in the diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases, and to discern connections between basic research and these relevant clinical conditions. This book addresses developmental, autoimmune, central, and peripheral neurodegeneration; infectious diseases; and diseases of higher function. The final chapters deal with broader issues, including some of the ethical concerns raised by neuroscience and a discussion of health disparities. Included in each chapter is coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. Written and edited by a diverse team of international experts, Neurobiology of Brain Disorders is essential reading for anyone wishing to explore the basic science underlying neurological and neuropsychiatric diseases. Links basic, translational, and clinical research on disorders of the nervous system, creating a format for study that will accelerate disease prevention and treatment Covers a vast array of neurological disorders, including ADHD, Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson, Huntington, Alzheimer, OCD, PTSD, schizophrenia, depression, and pain Illustrated in full color Each chapter provides in-text summary points, special feature boxes, and research questions Provides an up-to-date synthesis of primary source material

The American Psychiatric Publishing Textbook of Psychopharmacology

  • Filename: the-american-psychiatric-publishing-textbook-of-psychopharmacology.
  • ISBN: 9781585623099
  • Release Date: 2009
  • Number of pages: 1616
  • Author: Alan F. Schatzberg
  • Publisher: American Psychiatric Pub



Now updated to keep professionals current with the latest research and trends in the field, this edition covers both basic science and clinical practice, and draws on the talents of 53 new contributors to guarantee fresh, authoritative perspectives on advances in psychiatric drug therapy.

Schizophrenia and Related Disorders

  • Filename: schizophrenia-and-related-disorders.
  • ISBN: 9780199331505
  • Release Date: 2016-10-20
  • Number of pages: 280
  • Author: Michael J. Marcsisin
  • Publisher: Oxford University Press



Psychotic disorders are common and important psychiatric conditions, and patients suffering from psychosis can be challenging to assess and manage. In this new monograph, experts in schizophrenia and related psychoses review the current state of science in this area, and provide a practical and readable overview of the how to diagnose and treat individuals presenting with these disorders. This pocket-sized text features call-out boxes, case descriptions, practical tips, and general guidelines that should be ideal for medical students, residents, young mental health professionals, and trainees in other fields. Beginning with a history of psychosis, the authors proceed to explore the phenomenology of symptoms and experiences and how these can be used in clinical assessment. Diagnostic criteria are reviewed, along with common conditions in the differential diagnosis. Subsequent chapters tackle epidemiology, course and prognosis, and the neurobiology of psychotic disorders. The book concludes with chapters on treatment, both somatic and psychosocial, including discussion of novel interventional approaches and service delivery. The authors of this text are a mix of clinician-educators and scientific investigators, all with experience teaching trainees; this pocket-sized book has been developed to help young professionals easily gain a basic understanding of the complexities and challenges of psychotic disorders. Self-assessment questions, resources, and references will assist, but what really sets this book apart is the accessibility and concision of the text, ideal for individuals learning about or reviewing psychosis.

The Neurobiology of Childhood

  • Filename: the-neurobiology-of-childhood.
  • ISBN: 9783642549137
  • Release Date: 2014-05-13
  • Number of pages: 370
  • Author: Susan L. Andersen
  • Publisher: Springer



During the past years there has been rapid progress in the understanding of how early life stress impacts psychopathology in children. The first two parts of this book present the basic principles of brain development and describe the most important neuronal systems. This includes systems involved in emotion processing, cognitive control, and social processes. These first two general sections are followed by an overview about recent research on various neuronal and psychiatric disorders, where environmental exposures and altered brain development play an important role: sleep, autism, ADHD and other developmental forms of psychopathology.

Schizophrenia

  • Filename: schizophrenia.
  • ISBN: 9781444347746
  • Release Date: 2011-07-13
  • Number of pages: 736
  • Author: Daniel R. Weinberger
  • Publisher: John Wiley & Sons



Schizophrenia is one of the most complex and disabling diseases to affect mankind. Relatively little is known about its nature and its origins, and available treatments are inadequate for most patients. As a result, there are inevitable controversies about what causes it, how to diagnose it, and how best to treat it. However, in the past decade, there has been an explosion of new research, with dramatic discoveries involving genetic etiology and epidemiological risk factors. There has also been a catalog of new drugs coming to market, and controversy about the relative advantages and disadvantages of newer compared with older therapies. In addition, developing technologies in genomics, molecular biology and neuroimaging provide streams of new information. This book represents a definitive, essential, and up-to-date reference text on schizophrenia. It extensively and critically digests and clarifies recent advances and places them within a clinical context. The Editors (one American and one British), highly respected clinical psychiatrists and researchers and acknowledged experts on schizophrenia, have again assembled an outstanding group of contributors from the USA, UK, Europe and Australia, It will be of value to practising psychiatrists and to trainees, as well as to clinical and neuroscience researchers interested in keeping up with this field or coming into it. The book consists of four sections: descriptive aspects, biological aspects, physical treatments, and psychological and social aspects. It reviews the theoretical controversies over symptomatology, classification and aetiology (particularly pertinent as DSM-V is being developed), the relationship of schizophrenia to the other psychoses, the significance of positive and negative symptoms and pre-morbid personality. It describes a variety of approaches to integrating the vast research data about schizophrenia, including neurodevelopmental, genetic, pharmacological, brain imaging and psychological findings. The biological treatment section reviews the comparative efficacy of various drugs, the management of drug-resistant patients and both neurological and metabolic complications. The final section looks at psychological therapies, social outcomes, and the economics of schizophrenia. Highly Commended in the Psychiatry section of the 2012 BMA Book Awards.

Juvenile Onset Schizophrenia

  • Filename: juvenile-onset-schizophrenia.
  • ISBN: 1421403692
  • Release Date: 2011-03-07
  • Number of pages: 328
  • Author: Robert L. Findling
  • Publisher: JHU Press



This comprehensive overview of the phenomenology, epidemiology, pathology, and treatment of juvenile-onset schizophrenia will be useful to clinicians, researchers, and students.

Brain Protection in Schizophrenia Mood and Cognitive Disorders

  • Filename: brain-protection-in-schizophrenia-mood-and-cognitive-disorders.
  • ISBN: 904818553X
  • Release Date: 2010-06-16
  • Number of pages: 663
  • Author: Michael S. Ritsner
  • Publisher: Springer Science & Business Media



Neuroprotection is a novel perspective for the treatment of disorders that lead to neurodegeneration and disabilities as a result of deterioration of neurons due to apoptosis, oxidative stress, excitotoxicity, and other mechanisms. These mechanisms have implications not only for neurodegenerative disorders, but also for schizophrenia, mood and cognitive disorders. The purpose of this book is to provide an up-to-date overview of basic and clinical studies concerning the neuroprotective approach, mechanisms, and several compounds with neuroprotective properties that may contribute to more efficacious treatment of major mental health disorders. The book is divided into two sections. The first section serves as an introduction and overview of conceptual issues of the neuroprotective approach, and some neurobiological advances. Chapters in this section review definitions, perspectives, and issues that provide a conceptual base for the rest of the book. In addition, this part includes chapters in which the authors present and discuss the findings from basic studies of neurodegenerative mechanisms that are associated with the pathogenesis of major mental health disorders. The second section focuses on findings obtained from clinical trials with neuroprotective compounds, and neuromodulatory techniques. The take-home message is that principles of the neuroprotective approach may be applied to treatment of schizophrenia, mood and cognitive disorders. Contributors to this book are among the most active investigators and clinicians in the field who provide new perspectives not only clarifying ongoing controversies but also propose diverse aspects and new insights to neuroprotection. This book is intended for a broad readership, which includes a broad spectrum of readers including neuroscientists, psychiatrists, neurologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, graduate students, and policy makers in the fields of mental health.

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