The Bacteriophages

  • Filename: the-bacteriophages.
  • ISBN: 0198033850
  • Release Date: 2005-12-15
  • Number of pages: 768
  • Author: . Stephen T. Abedon
  • Publisher: Oxford University Press



This authoritative, timely, and comprehensively referenced compendium on the bacteriophages explores current views of how viruses infect bacteria. In combination with classical phage molecular genetics, new structural, genomic, and single-molecule technologies have rendered an explosion in our knowledge of phages. Bacteriophages, the most abundant and genetically diverse type of organism in the biosphere, were discovered at the beginning of the 20th century and enjoyed decades of used as anti-bacterial agents before being eclipsed by the antibiotic era. Since 1988, phages have come back into the spotlight as major factors in pathogenesis, bacterial evolution, and ecology. This book reveals their compelling elegence of function and their almost inconceivable diversity. Much of the founding work in molecular biology and structural biology was done on bacteriophages. These are widely used in molecular biology research and in biotechnology, as probes and markers, and in the popular method of assesing gene expression.

The Bacteriophages

  • Filename: the-bacteriophages.
  • ISBN: 0198033850
  • Release Date: 2005-12-15
  • Number of pages: 768
  • Author: . Stephen T. Abedon
  • Publisher: Oxford University Press



This authoritative, timely, and comprehensively referenced compendium on the bacteriophages explores current views of how viruses infect bacteria. In combination with classical phage molecular genetics, new structural, genomic, and single-molecule technologies have rendered an explosion in our knowledge of phages. Bacteriophages, the most abundant and genetically diverse type of organism in the biosphere, were discovered at the beginning of the 20th century and enjoyed decades of used as anti-bacterial agents before being eclipsed by the antibiotic era. Since 1988, phages have come back into the spotlight as major factors in pathogenesis, bacterial evolution, and ecology. This book reveals their compelling elegence of function and their almost inconceivable diversity. Much of the founding work in molecular biology and structural biology was done on bacteriophages. These are widely used in molecular biology research and in biotechnology, as probes and markers, and in the popular method of assesing gene expression.

Bacteriophages and Biofilms

  • Filename: bacteriophages-and-biofilms.
  • ISBN: 1617615889
  • Release Date: 2011
  • Number of pages: 138
  • Author: Stephen T. Abedon
  • Publisher: Nova Biomedical Books



Bacteriophages (phages) are the viruses of bacteria and biofilms that represent a frequent niche for bacteria, where they are embedded in extensive extracellular polymeric substances (EPS) and can be structured into complex microcolonies. As a consequence of the resulting spatial structure and heterogeneity, phage-bacterial interactions within biofilms can be more complicated than those between phages and planktonic bacteria. This book presents and discusses research which provides a better understanding of the biology of phages interacting with biofilms.

Bacteriophages in Health and Disease

  • Filename: bacteriophages-in-health-and-disease.
  • ISBN: 1845939859
  • Release Date: 2012
  • Number of pages: 296
  • Author: P. Hyman
  • Publisher: CABI



This book, Bacteriophages in health and disease, is an effort to provide an introduction to the breadth of roles that phages play or can play in our everyday lives. To capture this variety of phage roles in human conditions, both natural and applied, the book is divided into three parts. A brief introduction to various concepts and terminology associated with phages is provided in chapter 1. Part I (chapters 2-6) considers the role of phages in the natural state. That is, where phages are, how they contribute directly to disease, the underlying mechanism by which phages do this, and how they can contribute indirectly to disease, that is, to pathogen evolution. Part II (chapters 7-11) considers various phage-based technologies other than the use of whole phages to combat bacterial infections (i.e. besides phage therapy). This includes in particular the use of both modified and 'disembodied' phage parts. Phages thus can serve as carriers and delivery vehicles of DNA and also of other chemicals, including serving as vectors for either gene therapy or DNA vaccines. Part III (chapters 12-17) covers phage-based antibacterial strategies. It includes chapters on: phage translocation, safety and immunomodulation; phage therapy of wounds and related purulent infections; phage therapy of non-wound infections; phage-based enzybiotics; and phage-based control of bacterial pathogens in food. The final chapter of this book is targeted to would-be phage therapy experimentalists, one that considers, in light of phage properties, how phage therapy protocols may be developed in terms of the use of animal models of bacterial disease.

Bacteriophage Ecology

  • Filename: bacteriophage-ecology.
  • ISBN: 9781139471947
  • Release Date: 2008-05-01
  • Number of pages:
  • Author: Stephen T. Abedon
  • Publisher: Cambridge University Press



Bacteriophages, or phages, are viruses that infect bacteria and are believed to be the most abundant and genetically diverse organisms on Earth. As such, their ecology is vast both in quantitative and qualitative terms. Their abundance makes an understanding of phage ecology increasingly relevant to bacterial ecosystem ecology, bacterial genomics and bacterial pathology. Abedon provides the first text on phage ecology for almost 20 years. Written by leading experts, synthesizing the three key approaches to studying phage ecology, namely studying them in natural environments (in situ), experimentally in the lab, or theoretically using mathematical or computer models. With strong emphasis on microbial population biology and distilling cutting-edge research into basic principles, this book will complement other currently available volumes. It will therefore serve as an essential resource for graduate students and researchers, particularly those with an interest in phage ecology and evolutionary biology.

Bacteriophages

  • Filename: bacteriophages.
  • ISBN: UOM:39015075645476
  • Release Date: 2009
  • Number of pages: 308
  • Author: Martha R. J. Clokie
  • Publisher: Humana PressInc



Ranging from the evolution of pathogenicity to oceanic carbon cycling, the many and varied roles that bacteriophages play in microbial ecology and evolution have inspired increased interest within the scientific community. This book pulls together the vast body of knowledge and expertise from top international bacteriophage researchers to provide both classical and state-of-the-art molecular techniques. With its well-organized modular design, Volume 1 examines a multitude of topics, including the isolation of phages, morphological and molecular characterization, and interaction with bacteria. Volume 2 examines a multitude of topics, including the bacteriophage genomics, metagenomics, transcriptomics, and proteomics, along with applied bacteriophage biology. Written in the highly successful Methods in Molecular Biology series format, chapters consist of brief introductions to the subject, lists of the necessary materials and reagents, readily reproducible laboratory protocols, and a Notes section which details tips on troubleshooting and avoiding known pitfalls.

Bacteriophages

  • Filename: bacteriophages.
  • ISBN: 0203491750
  • Release Date: 2004-12-28
  • Number of pages: 528
  • Author: Elizabeth Kutter
  • Publisher: CRC Press



In response to the emergence of pathogenic bacteria that cannot be treated with current antibiotics, many researchers are revisiting the use of bacteriophages, or phages, to fight multidrug-resistant bacteria. Bacteriophages: Biology and Applications provides unparalleled, comprehensive information on bacteriophages and their applications, such as phage therapy. It offers techniques, media, and methodology involved in isolating and working with therapeutic phages. Photographs, line drawings, and electron micrographs of phages are also included. With its broad approach, this book is a useful reference for microbiologists, hematologists, and infectious disease researchers.

Bacteriophage

  • Filename: bacteriophage.
  • ISBN: 9781904455141
  • Release Date: 2007
  • Number of pages: 343
  • Author: Stephen Mc Grath
  • Publisher: Horizon Scientific Press



Bacteriophages (viruses that infect bacteria) are fascinating organisms that have played and continue to play a key role in bacterial genetics and molecular biology. Phage can confer key phenotypes on their host - for example, converting a non-pathogenic strain into a pathogen - and they play a key role in regulating bacterial populations in all sorts of environments. The phage-bacterium relationship varies enormously, from the simple predator-prey model to a complex, almost symbiotic relationship that promotes the survival and evolutionary success of both. While infection of bacteria used in the fermentation industry can be very problematic and result in financial losses, in other scenarios, phage infection of bacteria can be exploited for industrial and/or medical applications. Interest in phage and phage gene products as potential therapeutic agents is increasing rapidly and is likely to have a profound impact on the pharmaceutical industry and biotechnology in general over the coming years. One potential application is the use of phage to combat the growing menace of antibiotic-resistant infections. Written by eminent international researchers actively involved in the disparate areas of bacteriophage research, this book focuses on the current rapid developments in this exciting field. The book opens with an excellent chapter that provides a broad overview of the topics and also highlights the multifaceted nature of bacteriophage research. This is followed by a series of reviews that focus on the current, most cutting-edge topics including bioinformatics and genomics, phage in the environment, bacteriophage in medicine, transfer of phage DNA to the host, contribution to host phenotype, and much more. The book will be essential reading for all phage researchers and of interest to molecular biologists and microbiologists working on bacteria in academia, biotechnology, and pharmaceutical companies, as well as in the food industry.

Biological Management of Diseases of Crops

  • Filename: biological-management-of-diseases-of-crops.
  • ISBN: 9789400763807
  • Release Date: 2013-06-28
  • Number of pages: 673
  • Author: P. Narayanasamy
  • Publisher: Springer Science & Business Media



Biological disease management tactics have emerged as potential alternative to chemical application for containing crop diseases. Biotic and abiotic biological control agents (BCAs) have been demonstrated to be effective against diseases caused by microbial plant pathogens. Combination of biotic and abiotic agents leads to synergism and consequent improvement in the effectiveness of disease control. It is essential to assay the biocontrol potential of all isolates/species of fungal, bacterial and viral biocontrol agents by different techniques in vitro and under greenhouse and field conditions and to precisely identify and differentiate the most effective isolates from less effective ones by employing biological, immunological and nucleic acid-based assays.

Bacteriophages

  • Filename: bacteriophages.
  • ISBN: 0203491750
  • Release Date: 2004-12-28
  • Number of pages: 528
  • Author: Elizabeth Kutter
  • Publisher: CRC Press



In response to the emergence of pathogenic bacteria that cannot be treated with current antibiotics, many researchers are revisiting the use of bacteriophages, or phages, to fight multidrug-resistant bacteria. Bacteriophages: Biology and Applications provides unparalleled, comprehensive information on bacteriophages and their applications, such as phage therapy. It offers techniques, media, and methodology involved in isolating and working with therapeutic phages. Photographs, line drawings, and electron micrographs of phages are also included. With its broad approach, this book is a useful reference for microbiologists, hematologists, and infectious disease researchers.

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