How Proteins Work

  • Filename: how-proteins-work.
  • ISBN: 0815344465
  • Release Date: 2012
  • Number of pages: 464
  • Author: Michael Paul Williamson
  • Publisher: Garland Pub



How Proteins Work is an up-to-date and authoritative account of protein function in living systems, explained within the governing parameters of physics, chemistry, and evolution. This text will enable advanced undergraduate students in biochemistry and biophysics to understand the relationships among protein function, structure, and dynamics. It will also serve as a valuable resource for graduate students and researchers looking for a reference on the fundamentals underlying protein function. By providing an integrated view of proteins at both a cellular and systemic level, this textbook shows how evolution drives proteins to adopt domain structures that combine to achieve biological outcomes. The association of proteins into dimers, molecular machines, and multi-enzymatic complexes enables them to achieve catalytic and functional efficiency.

How Proteins Work

  • Filename: how-proteins-work.
  • ISBN: 9781136665493
  • Release Date: 2011-07-20
  • Number of pages: 464
  • Author: Michael Williamson
  • Publisher: Garland Science



How Proteins Work is an up-to-date and authoritative account of protein function in living systems, explained within the governing parameters of physics, chemistry, and evolution. This text will enable advanced undergraduate students in biochemistry and biophysics to understand the relationships among protein function, structure, and dynamics. It will also serve as a valuable resource for graduate students and researchers looking for a reference on the fundamentals underlying protein function. By providing an integrated view of proteins at both a cellular and systemic level, this textbook shows how evolution drives proteins to adopt domain structures that combine to achieve biological outcomes. The association of proteins into dimers, molecular machines, and multi-enzymatic complexes enables them to achieve catalytic and functional efficiency.

Molecular Biology of the Cell

  • Filename: molecular-biology-of-the-cell.
  • ISBN: 0824036956
  • Release Date: 1989
  • Number of pages: 1263
  • Author: Bruce Alberts
  • Publisher: Courier Corporation



New edition of a text in which six researchers from leading institutions discuss what is known and what is yet to be understood in the field of cell biology. The material on molecular genetics has been revised and expanded so that it can be used as a stand-alone text. A new chapter covers pathogens, infection, and innate immunity. Topics include introduction to the cell, basic genetic mechanisms, methods, internal organization of the cell, and cells in their social context. The book contains color illustrations and charts; and the included CD-ROM contains dozens of video clips, animations, molecular structures, and high-resolution micrographs. Annotation copyrighted by Book News Inc., Portland, OR.

Essential Cell Biology Fourth Edition

  • Filename: essential-cell-biology-fourth-edition.
  • ISBN: 9781317806271
  • Release Date: 2013-10-15
  • Number of pages: 865
  • Author: Bruce Alberts
  • Publisher: Garland Science



Essential Cell Biology provides a readily accessible introduction to the central concepts of cell biology, and its lively, clear writing and exceptional illustrations make it the ideal textbook for a first course in both cell and molecular biology. The text and figures are easy-to-follow, accurate, clear, and engaging for the introductory student. Molecular detail has been kept to a minimum in order to provide the reader with a cohesive conceptual framework for the basic science that underlies our current understanding of all of biology, including the biomedical sciences. The Fourth Edition has been thoroughly revised, and covers the latest developments in this fast-moving field, yet retains the academic level and length of the previous edition.

How Proteins Search for Their Targets on DNA

  • Filename: how-proteins-search-for-their-targets-on-dna.
  • ISBN: 9780549585534
  • Release Date: 2008
  • Number of pages: 169
  • Author:
  • Publisher: ProQuest



We further extended our theory to the macroscopic diffusion coefficient of proteins in a semi-dilute solution of DNA pieces and the effective conductivity of a composite made of well conducting nanowires suspended in some poor conducting medium.

Soliton Theory

  • Filename: soliton-theory.
  • ISBN: 0719014913
  • Release Date: 1990-01-01
  • Number of pages: 449
  • Author: Allan P. Fordy
  • Publisher: Manchester University Press



A coherent introduction to the complete range of soliton theory including Hirota's method and Backlund transformations. Details physical applications of soliton theory with chapters on the peculiar wave patterns of the Andaman Sea, atmospheric phenomena, general relativity and Davydov solitons. Contains testing for full integrability, a discussion of the Painlevé technique, symmetries and conservation law.

Fundamentals of Protein Structure and Function

  • Filename: fundamentals-of-protein-structure-and-function.
  • ISBN: 9780387684802
  • Release Date: 2007-08-28
  • Number of pages: 367
  • Author: Engelbert Buxbaum
  • Publisher: Springer Science & Business Media



The textbook is clearly written, and is suitable for advanced students, e.g. during their master and PhD course time. It is very suited also for postdocs and young scientists as a textbook if they change fields in their research. The textbook represents a thorough and detailed description of the topics in each of the chapters. As the book selects very important topics of present fundamental research and relevant in medical biochemistry, it can supplement any of the text books in biochemistry and basic medicine already on the market. The textbook is clearly written, and is suitable for advanced students, e.g. during their master and PhD course time. It is very suited also for postdocs and young scientists as a textbook if they change fields in their research. The textbook represents a thorough and detailed description of the topics in each of the chapters. As the book selects very important topics of present fundamental research and relevant in medical biochemistry, it can supplement any of the text books in biochemistry and basic medicine already on the market.

Encyclopedia of Metalloproteins

  • Filename: encyclopedia-of-metalloproteins.
  • ISBN: 1461415322
  • Release Date: 2013-05-01
  • Number of pages: 2574
  • Author: Robert H. Kretsinger
  • Publisher: Springer



In biochemistry, a metalloprotein is a generic term for a protein that contains a metal cofactor. The metal may be an isolated ion or may be coordinated with a nonprotein organic compound, such as the porphyrin found in hemoproteins. In some cases, the metal is co-coordinated with a side chain of the protein and an inorganic nonmetallic ion. This kind of protein-metal-nonmetal structure is seen in iron-sulfur clusters Metalloproteins deals with all aspects related to the intracellular and extracellular metal-binding proteins, including their structures, properties and functions. The biological roles of metal cations and metal-binding proteins are endless. They are involved in all crucial cellular activities. Many pathological conditions are related to the problematic metal metabolism. Research in metalloprotein-related topics is therefore rapidly growing, and different aspects of metal-binding proteins progressively enter curricula at Universities and even at the High School level on occasion. However, no key resource providing basic, but comprehensible knowledge on this rapidly expanding field exists. The Encyclopedia of Metalloproteins aims to bridge this gap, and will attempt to cover various aspects of metalloprotein/metalloproteomics and will deal with the different issues related to the intracellular and extracellular metal-binding proteins, including their structures, properties and functions. The goal is to cover exhaustively all catalytically and biologically crucial metal ions and to find at least one interacting protein for other metal ions. The Encyclopedia of Metalloproteins will provide a key resource for advanced undergraduate and graduate students, researchers, instructors, and professors interested in protein science, biochemistry, cell biology, and genetics.

Localization Energy Transfer in Nonlinear Systems

  • Filename: localization-energy-transfer-in-nonlinear-systems.
  • ISBN: 9812704620
  • Release Date: 2003
  • Number of pages: 351
  • Author: Robert Sinclair MacKay
  • Publisher: World Scientific



This conference was the third meeting organized in the framework of the European LOCNET project. The main topics discussed by this international research collaboration were localization by nonlinearity and spatial discreteness, and energy transfer (in crystals, biomolecules and Josephson arrays).

Milk Proteins

  • Filename: milk-proteins.
  • ISBN: 9780080920689
  • Release Date: 2009-02-07
  • Number of pages: 552
  • Author: Abby Thompson
  • Publisher: Academic Press



In recent years, there has been a great deal of progress in the understanding and management of milk proteins across the production chain. This book takes a uniquely comprehensive look at those developments and presents them in a one-source overview. By providing a brief overview of each topic area, and then describing the most important recent advances therein, the "field-to-table" approach of this book provides specialists with new and directly relevant information in their own areas, along with information from complementary research fields, allowing them to contextualize their work within the larger pictures. At the same time it provides generalists with a complete overview and offers insights into topics for more in-depth reading. Covering areas that are receiving attention from people of many fields -- genomics, functional foods -- and including the latest research and developments in milk-protein phenomenon and interactions, this book will be an ideal resource for professionals and students alike. *A fresh look at recent developments across the entire production chain -- from animal genetics to nutritional and nutrigenomic needs of the customer *Up-to-date information from internationally-recognised authors from both academic and commercial resources

Bacterial Protein Toxins

  • Filename: bacterial-protein-toxins.
  • ISBN: UOM:39015056663282
  • Release Date: 2003
  • Number of pages: 348
  • Author: Drusilla L. Burns
  • Publisher: Amer Society for Microbiology



Designed for newcomers to the field of toxins and is intended to show how proteins work and how they can be used in research. Describes all aspects of the biology of toxins, including their synthesis and secretion from the bacterial cell. Their travels to and into the target host cell, and their modes of attacking the host cell machinery. Illustrates how bacterial toxins, each of which has distinct individual properties, often share mechanisms of secretion, membrane transport and enzymatic action.

Non Natural Amino Acids

  • Filename: non-natural-amino-acids.
  • ISBN: 0080921639
  • Release Date: 2009-07-24
  • Number of pages: 350
  • Author:
  • Publisher: Academic Press



By combining the tools of organic chemistry with those of physical biochemistry and cell biology, Non-Natural Amino Acids aims to provide fundamental insights into how proteins work within the context of complex biological systems of biomedical interest. The critically acclaimed laboratory standard for 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. With more than 400 volumes published, each Methods in Enzymology volume presents material that is relevant in today's labs -- truly an essential publication for researchers in all fields of life sciences. Demonstrates how the tools and principles of chemistry combined with the molecules and processes of living cells can be combined to create molecules with new properties and functions found neither in nature nor in the test tube Presents new insights into the molecular mechanisms of complex biological and chemical systems that can be gained by studying the structure and function of non-natural molecules Provides a "one-stop shop" for tried and tested essential techniques, eliminating the need to wade through untested or unreliable methods

A Positron Named Priscilla

  • Filename: a-positron-named-priscilla.
  • ISBN: 9780309048934
  • Release Date: 1994-01-01
  • Number of pages: 360
  • Author: Addison Greenwood
  • Publisher: National Academies Press



A Positron Named Priscilla is a book of wonder, offering a fascinating, readable overview of cutting-edge investigations by many of today's leading young scientists. Written for anyone who loves science, this volume reports on some of the most exciting recent discoveries and advances in fields from astronomy to molecular biology. This new book is from one of the world's most prestigious scientific institutions, the National Academy of Sciences. The Academy provides an annual forum for the brightest young investigators to exchange ideas across disciplines--an exchange that was the spark for A Positron Named Priscilla. Each chapter is authored by a popular science writer who offers helpful historical perspectives, clear and well-illustrated explanations of current scientific thinking, and previews of future developments. The scope of topics and breadth of discussion ensure interest at all levels. Topics include Planetary science and the compelling glimpse through the clouded atmosphere of Venus afforded by the spacecraft Magellan. Astrophysics and the emergence of helioseismology, a new field that allows researchers to probe the interior workings of the sun. Biology and what we have learned about DNA in the 40 years since its discovery; our current understanding of protein molecules, the "building blocks" of living systems; and the high-tech search for answers to the AIDS epidemic. Physics and our new-found ability to move and manipulate individual atoms on a surface. The book also tells the remarkable story of "buckyballs," or buckminsterfullerenes, a form of carbon discovered only a few years ago, that have the potential to be used in a variety of important applications, from superconductivity to nanotechnology. Mathematics and the rise of "wavelet" theory, and how mathematicians are applying it in sometimes startling ways, from assisting the FBI with fingerprint storage to coaxing the secrets from a battered recording of Brahms playing the piano. Geosciences and the search for "clocks in the earth" to make life-saving earthquake predictions. A Positron Named Priscilla is a "must" read for anyone who wants to keep up with a broad range of scientific endeavor.

Methods in Proteome and Protein Analysis

  • Filename: methods-in-proteome-and-protein-analysis.
  • ISBN: 3540202226
  • Release Date: 2004-01-23
  • Number of pages: 404
  • Author: Roza Maria Kamp
  • Publisher: Springer Science & Business Media



Following the succesful publication of "Proteome and Protein Analysis" in 2000, which was based on a former MPSA (Methods in Protein Structure Analysis) conference, "Methods in Proteome and Protein Analysis" presents the most interesting papers from the 14th MPSA meeting. Selected contributions discuss the latest techniques and approaches for analysing protein and proteome structures. Major topics include: protein and peptide sample preparation and separation new reagent for protein sequence analysis mass spectrometry in protein research analysis of posttranslational modification protein-protein interaction using MALDI-MS manipulation of genome or functional compositon trap structure-function correlation study using optical biosensors of microcolorimetrical techniques structural proteomics as NMR or fluorescence polarization study the classification and prediction of structure or functional sites in silico analysis of proteins and proteomes increasing throughput and data quality for proteomics

Membrane Structural Biology

  • Filename: membrane-structural-biology.
  • ISBN: 9781107729339
  • Release Date: 2014-02-24
  • Number of pages: 400
  • Author: Mary Luckey
  • Publisher: Cambridge University Press



This textbook provides a strong foundation and a clear overview for students of membrane biology and an invaluable synthesis of cutting-edge research for working scientists. The text retains its clear and engaging style, providing a solid background in membrane biochemistry, while also incorporating the approaches of biophysics, genetics and cell biology to investigations of membrane structure, function and biogenesis to provide a unique overview of this fast-moving field. A wealth of new high resolution structures of membrane proteins are presented, including the Na/K pump and a receptor-G protein complex, offering exciting insights into how they function. All key tools of current membrane research are described, including detergents and model systems, bioinformatics, protein-folding methodology, crystallography and diffraction, and molecular modeling. This comprehensive and up-to-date text, emphasising the correlations between membrane research and human health, provides a solid foundation for all those working in this field.

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